McCarthy was born in Evergreen Park, Illinois to a middle-class Catholic family of Polish and Irish descent. She lived in the West Elsdon neighborhood of Chicago. She is the second of four daughters; her sisters are named Lynette, Joanne and Amy. Her cousin is Academy Award-nominated actress Melissa McCarthy of Bridesmaids and Mike and Molly. McCarthy's mother, Linda, was a housewife and courtroom custodian, and her father, Dan McCarthy, was a steel mill foreman.
As a teenager, McCarthy attended Mother McAuley Liberal Arts High School (whose school sweater she donned in the pages of Playboy) and was a cheerleader at both Brother Rice High School and St. Laurence High Schools, although she has referred to herself as an "outcast" at her school and has described how she was repeatedly bullied by classmates.
Modeling and acting
After getting accepted by Playboy in 1993, the magazine offered McCarthy $20,000 (equivalent to $32,177 today) to pose for its October issue. McCarthy became the Playmate of the Month and later the Playmate of the Year and was paid a $100,000 salary. In 1994, because of her newfound public attention, McCarthy moved to Los Angeles and, for a time, hosted Hot Rocks, a Playboy TV show featuring uncensored music videos.
In 1995, MTV chose McCarthy to be the host of a new dating show called Singled Out, for which she left Hot Rocks. Her job as a host was a success, and Playboy wanted her to do more modeling. That same year, she also appeared at World Wrestling Federation (WWF) pay-per-view event WrestleMania XI as a guest valet for villain Shawn Michaels, who faced heroic WWF Champion, Diesel. She left after the match with the victor, Diesel. McCarthy returned to World Wrestling Entertainment (WWE, formerly the WWF) on the August 2, 2008 edition of Saturday Night's Main Event to thank the fans for supporting Generation Rescue, an autism advocacy organization. In 1996, she landed a small part in the comedy The Stupids. In 1997, McCarthy launched two shows. The first one was an MTV sketch comedy show The Jenny McCarthy Show, which was sufficiently popular for NBC to sign her for an eponymous sitcom later that year, Jenny. The latter show is generally considered a disappointment and was quickly canceled. Also in 1997, she appeared on one of two covers for the September issue of Playboy (the other cover featured Pamela Anderson). McCarthy also released an autobiography: Jen-X: Jenny McCarthy's Open Book.
In 1998, McCarthy's first major movie role was alongside Trey Parker and Matt Stone in the comedy BASEketball. The following year, she starred in Diamonds, a movie which was directed by her then-husband John Mallory Asher. In 2000, she had a role in the horror movie Scream 3, and three years later she parodied that role in horror film spoof Scary Movie 3 along with fellow Playmate and actress Pamela Anderson. In 2005, McCarthy produced, wrote, and starred in the movie Dirty Love, where she was again directed by her husband at the time, John Asher. In March 2006, she was given Razzie Awards for "Worst Actress", "Worst Screenplay", and "Worst Picture" for her work on Dirty Love, which also earned Asher a Razzie for "Worst Director."
In addition to her early TV fame on MTV and her short-lived, self-titled NBC sitcom, McCarthy has guest starred in a variety of other television shows including Stacked, Charmed, The Drew Carey Show, Wings, Fastlane, Two and a Half Men and Just Shoot Me!. She was the voice of Six in the third season of Canadian computer-animated science fiction cartoon Tripping the Rift. In 2005, McCarthy hosted a show on E! called Party at the Palms. The reality show, which was filmed at The Palms Hotel in Las Vegas, featured hotel guests, party goers, and celebrities.
McCarthy has continued her work with Playboy over the years, both as a model and in other capacities. She appeared on the cover of the magazine's January 2005 issue wearing a leopard skin version of the company's iconic "bunny suit" and was featured in a pictorial shot at Elvis Presley's Graceland mansion in that same issue. She was the second woman (following Carmen Electra) and first former Playmate to become a celebrity photographer for the Playboy Cyber Club, where she photographed model Jennifer Madden.
In 2007, McCarthy starred in a five-episode online series, called In the Motherhood, along with Chelsea Handler and Leah Remini. The show aired on MSN and was based on being a mother where users could submit their stories to have it made into real webisodes.
She has also appeared in two video games: playing the role of Agent Tanya in the video game Command and Conquer: Red Alert 3, replacing Kari Wührer, and the fitness video game Your Shape Featuring Jenny McCarthy.
On December 31, 2010, McCarthy was a correspondent in Times Square for ABC's Dick Clark's New Year's Rockin' Eve.
She is the host of season 2 of Love in the Wild, which began on June 7, 2012.
McCarthy once modeled for Candie's, a shoe company. In one magazine ad, McCarthy posed on a toilet seat with her underwear near her ankles. Cultural scholar Collin Gifford Brooke wrote that the ad's "taboo nature" brought it attention, while noting that the ad itself helped to weaken that taboo.Another Candie's ad depicted McCarthy passing wind in a crowded elevator.
This theme was taken to a new extreme in her film Dirty Love, which featured McCarthy's character sitting in a massive pool of her own menstrual blood.
Source : http://en.wikipedia.org/wiki/Jenny_McCarthy